General Manager, Product (B2B2C)

About Keystone AI : Keystone AI is on a mission to make heart attacks a thing of the past. We’re an AI company focused exclusively on heart health, building a platform that predicts and prevents cardiac events before they happen—identifying risk up to 10 days in advance versus 10 years in traditional clinical models. This is already working at scale. Keystone AI has been shown to reduce inpatient hospital days by 47% and deliver ~$1,800 in annual savings per member. Keystone AI is the cardiac prevention partner to over 80% of large U.S. health plans and serves hundreds of public and private employers. We’re defining how the #1 cause of death—heart disease—is managed in the AI era. Join us. About the Role: Keystone AI is seeking a General Manager, Product (B2B2C) to build, and scale the next generation of AI-powered healthcare businesses that transform the future of cardiovascular care. This is a unique opportunity to operate as a business builder within a rapidly growing digital health company. You will own the strategy, product vision, go-to-market approach, growth, and overall success of a new product line from concept through scale. Reporting to the Chief Product & Technology Officer, you will work across Product, Engineering, Clinical, Data, Compliance, Sales, Marketing, Customer Success, and Product Marketing to transform market opportunities into meaningful member outcomes and sustainable business growth. The ideal candidate combines strong product leadership with commercial saviness , consumer expertise, and a founder-like mentality. You are energized by ambiguity, thrive in zero-to-one environments, and know how to turn insights into scalable products that customers buy and members love. Must be located in an Eastern Time Zone state or be willing to consistently work Eastern Time hours to support collaboration with our Tel Aviv colleagues. Responsibilities: Define and own the end-to-end product strategy, roadmap, go-to-market strategy, and success metrics for a new B2B2C product line Identify growth opportunities and drive product-market fit, adoption, and expansion. Build AI-first healthcare solutions that improve member outcomes and operational efficiency. Lead product development across software, services, AI capabilities, and connected devices. Partner with Sales, Marketing, and Customer Success to drive customer growth. Define and execute launch, positioning, and adoption strategies. Establish operating rhythms, performance dashboards, customer feedback loops, and market learning systems to measure impact and improve the product over time Qualifications: Strong AI fluency and experience applying AI to products, workflows, or operations. 10+ years of product management, product leadership, or related leadership experience, including experience leading teams Proven track record building and scaling a product line from zero to one and one to one hundred in a fast-paced, high-growth environment Experience building and driving go-to-market strategy for a new product, including early market validation, positioning, launch planning, adoption strategy, and product-market fit Experience building digital health, healthcare technology, care management, or clinically aligned products - a plus Strong systems thinking, with the ability to create repeatable processes, operating models, and scalable product infrastructure Exceptional communication skills, with the ability to simplify complex information for executive, technical, clinical, commercial, and cross-functional audiences The US base salary range for this full-time position is $260,000.00 to $280,000.00. Salary ranges are determined by role and level. Compensation is determined by additional factors, including job-related skills, experience, and relevant education or training. Please note that the compensation details listed in US role postings reflect the annual salary and bonus only, and do not include equity or benefits. Keystone AI has a positive, diverse, and supportive culture - we look for people who are collaborative, creative, and courageous. Oh, and if you want to see some recent evidence of the fun things we do at Keystone AI , check out our Instagram page . Originally posted on Himalayas