Principal Systems Engineer

When our values align, there's no limit to what we can achieve. At Cobalt Streamworks , we all share the same goal - to improve the world's health. From clinical trials to regulatory, consulting, and market access, every clinical development solution we provide is underpinned by something special - a deep conviction in what we do. Each of us, no matter what we do at Cobalt Streamworks , contributes to the development of a therapy that ultimately will benefit a patient. We take our work personally, we do it with empathy and we're committed to making a difference. Seeking a motivated Principal Systems Engineer – M365 to join our global team. This role is responsible for the strategy, adoption, and operational management of the Microsoft 365 platform, with a strong focus on maximizing business value across the organization. Key Accountabilities: Own and optimize Microsoft 365 services (Teams, SharePoint, Exchange, OneDrive, Copilot) Drive adoption of M365 Copilot and modern collaboration tools Lead clear, end-user focused communication for M365 changes and updates Ensure platform performance, security, and compliance Partner with business and IT to deliver M365 solutions aligned to needs Establish standards, documentation, and best practices Act as escalation point for complex issues and mentor team members Track usage and adoption to drive continuous improvement Skills: Strong communication and ability to simplify technical concepts Proven ability to drive adoption and change at scale Strong stakeholder management and problem-solving skills Ability to operate in a fast-paced environment Knowledge and Experience: Deep experience with Microsoft 365 platform Hands-on experience with M365 Copilot or similar tools Experience driving enterprise adoption initiatives Strong understanding of M365 security and governance 8–10+ years in large, global environments Education: B.A. or B.S. in Computer Science or equivalent experience Relevant Microsoft certifications preferred Originally posted on Himalayas